A Gene-Smart Lifestyle

While we were all created unique, we are actually 99.9% identical on a DNA level. The remaining 0.1% of the human genome, which relates to 3 million "letters" of the genetic code, is responsible for all the visible and hidden differences. Nutrigenomics is the scientific discipline that studies the interaction between your genes, diet and lifestyle. Your genes are your body's blueprint for what you look like to your susceptibility to disease. Genes determine the way your body responds to food and physical activity. The science of nutrigenomics has changed the way we approach weight and health management, we are now able to personalise dietary recommendations based upon your unique genetic profile. Science has made it possible to personalise your nutrition, and change the message to your genes to minimise your risk for disease.

Why Nutrigenomics?

  1. Poor diet increases your risk for chronic disease.
  2. What you eat can change your gene expression.
  3. How diet influences the balance between health and disease depends on your genetic make-up.
  4. Some diet-regulated genes play a role in the onset, progression and severity of certain diseases.
  5. Dietary recommendation based on the knowledge of nutritional requirements, nutritional status and genetic make-up can prevent and reduce the onset of chronic disease.

Maximise Your Genetic Potential

Your genetic risk is not absolute, so you are not a victim of your genes! We all have a mixture of "good" and "bad" traits embedded in our genes, but no genetic message is etched in stone. Your individual genetic profile, together with how you choose to live (what you eat, drink, sleep, exercise and breathe), are the major determinants of how your risk will play out over time. When you gather the information you need to make healthier choices, you empower yourself and optimise your individual potential. You are in control and you can change these genetic messages by making better and healthier nutritional choices - in the process you change your genetic destiny!

How the process works

During a consultation your medical history and current medical concerns are discussed (this may include a physical assessment, nutrition analysis and assessment of environmental and other lifestyle factors that may affect your health) as well as a the test explained, and which test will be most suitable for you. A test kit can be delivered to your home or office, ideally we will do the test sample in my office. The test kit includes oral swabs with instructions, which will be picked up by a courier company and sent for analysis. After a few weeks a report will be sent to you and a copy to me.

How do we help?

Once I receive the genetic test results, I will be able to link your genetic predisposition with current health concerns or disease prevention as well as specific dietary adjustments that need to be made. The results provide the clinical information upon which I translate your genetic information into practical prescriptions for personalised health care, including what exercises to do, your tendency to certain injuries and how to prevent that, what foods to avoid and what to include. It is often a lot of information to take in during one session, so we break the sessions up over a couple of weeks in which we guide your through making these lifestyle and dietary adjustments. You will be provided with a full report on key metabolic areas to focus on, key nutritional changes you have to make and key nutraceutical recommendations and lifestyle changes necessary to create your path to improved health.

You will be able to maximise your health and well-being through:

  • optimal weight loss
  • optimal weight management
  • optimal dietary modifications
  • optimal lifestyle improvements such as type and amount of exercise required

DNA Tests and What They Test

There are currently 2 Genetic Testing companies that we use,

  1. DNAlysis        www.dnalysis.co.za                      
  2. 3X4 Genetics www.3x4genetics.io                     Click here for a product brochure

dna diet designed to optimise your weight loss and exercise programme based on the genetic information of your metabolism, lipolysis (the breakdown of fats and other lipids) and fat absorption.

It provides insight into:

  • individual diet and exercise responsiveness
  • optimal macronutrient (Fats, Carbohydrates and Proteins) distribution for excellent weight loss
  • weight-loss resistance and/or weight gain after weight loss
  • optimal exercise intensity for weight loss/ weight management

dna health is concerned with improving energy, well-being and health through improved lifestyle and food choices as well as using the correct supplements to offset the nutritional deficits or genetic shortcomings. This panel also establishes the optimal nutrition necessary for longevity and risk reduction. Some individuals have increased requirements for certain nutrients, such as folic acid, calcium, vitamin D or omega-3 fatty acids, which may require supplementation. The test will also show whether a person will be able to reduce cholesterol levels through diet, instead of medication, etc.  DNA Health tests for 27 genes involved in the following biological processes:

  • cholesterol regulation
  • bone health
  • vitamin B metabolism/ methylation
  • inflammation
  • detoxification
  • antioxidant status
  • insulin sensitivity

dna sport tests genes that  relate to your sporting performance. The Power and Endurance section tests genes that affect physiological factors such as:

  • circulation
  • blood pressure
  • strength
  • cardio pulmonary capacity
  • mitochondrial synthesis (how you make energy)
  • muscle fibre type and hypertrophy
  • cardiac output
  • muscle metabolism and adaptability to different training regimes

The Tendon Pathology section looks at genes that are involved in your body's structural integrity of soft tissue and looks at your predisposition to

  • tendon injuries (incl. Achilles Tendinitis)
  • ligament pathology
  • cartilage and bone pathologies

The Recovery genes will highlight the need to integrate training and nutritional advice. This panel looks at genes regulating inflammation and free radical stress within the body, which may require focused nutritional changes together with longer recovery periods between training sessions.

dna oestrogen Oestrogen hormones play a role in the growth, differentiation and function of a number of tissues.  If you are oestrogen dominant or have any of the following you will benefit from improving your oestrogen metabolism:

  • endometriosis
  • PMS
  • uterine fibroid tumours
  • family history of breast, uterine or ovarian cancer
  • prostate cancer in men

Understanding your genetic variation will allow targeted diet, lifestyle and hormone intervention.

mygeneRx is a new addition to DNAlysis biotechnology portfolio. This panel of genes look at how your body metabolises certain classes of medication and what will work best for you. It ensures safe and effective prescription of medication, it takes the guess work out of your prescription.

dna skin involves analysing variations on 18 genes associated with skin health and aging and look at the following key areas:

  • collagen formation
  • protection from sun and uv exposure
  • inflammation
  • protection from oxidative stress

Based on these results, personalised advice and recommendations on lifestyle, nutrition, nutraceutical and comeceutical recommendations to decrease visible signs of aging.